Endometriosis IUI & IVF
This training video will discuss how endometriosis can significantly impact fertility and challenge patients seeking IUI or IVF treatments. A thorough understanding of the condition, combined with individualized treatment plans, can help improve the chances of successful conception.
Understanding Endometriosis
- Chronic condition where endometrial tissue grows outside the uterus
- Symptoms include dysmenorrhea, dyspareunia, and infertility
- Retrograde menstruation and immune system dysfunction as potential causes
Endometriosis and Fertility
Ovarian function and egg quality
Reduced ovarian reserve
Impaired follicular development
Altered hormonal environment
Endometriomas and dermoid cysts
Benign ovarian growths
Adversely affect ovarian function
May require surgical removal
Inflammation and adhesions
Pelvic inflammation due to endometriosis
Formation of scar tissue and adhesions
Obstruction or distortion of fallopian tubes and pelvic organs
Compromise natural conception and fertility treatments
Antral Follicle Count (AFC) and Ovarian Reserve
Assessment of ovarian reserve in endometriosis patients
Non-invasive ultrasound evaluation
Determines the number of small, developing follicles
Indicator of a woman’s reproductive potential
European Society of Human Reproduction and Embryology (ESHRE) guidelines
Standardization of AFC measurement
Ensures accuracy and comparability
Helps tailor fertility treatments to individual patients
Intrauterine Insemination (IUI) for Endometriosis Patients
Ovulation induction with FSH and LH
FSH and LH medications
Stimulate follicle development
Enhance ovulation for timed insemination
Progesterone supplementation for luteal phase support (LPS)
Progesterone supplementation
Promotes endometrial receptivity
Increases chances of implantation
Best suited for mild endometriosis cases
IUI most effective in less severe cases
Minimal impact on fallopian tubes and pelvic organs
Higher success rates compared to moderate or severe endometriosis
Luteal Phase Deficiency (LPD) and Gonadotrophin Treatment
Importance of progesterone for endometrial receptivity
Essential for preparing the uterus
Supports implantation and early pregnancy
Gonadotrophin therapy to improve pregnancy outcomes
FSH and LH medications
Stimulates follicle development and ovulation
Enhances luteal phase hormone levels
Improves chances of successful pregnancy
In Vitro Fertilization (IVF) for Endometriosis Patients
Moderate to severe endometriosis
More extensive pelvic adhesions and cysts
Reduced fertility due to tubal or ovarian dysfunction
IVF bypasses fallopian tubes, increasing chances of conception
Poor ovarian reserve (POR)
Limited number of available eggs
Controlled ovarian hyperstimulation during IVF
Maximizes the number of eggs retrieved for fertilization
Removal of endometriomas via cystectomy prior to IVF
Surgical procedure to excise ovarian cysts
Reduces inflammation and improves ovarian function
Optimizes the environment for successful IVF treatment
Potential use of egg donation in cases of premature ovarian failure (POF)
POF results in a diminished or depleted egg supply
Egg donation offers an alternative path to parenthood
Healthy donor eggs increase the likelihood of IVF success
IVF Success Rates and Endometriosis
Lower success rates compared to other causes of infertility
Importance of individualized treatment plans and proactive management
Improving Fertility Outcomes for Endometriosis Patients
Surgical intervention to remove endometriomas and adhesions
Hormonal suppression therapy to minimize endometriosis symptoms
Lifestyle modifications and pain management strategies
Fertility Supplements for Endometriosis Patients
Coenzyme Q10, DHEA, and Melatonin for improved egg quality
Antioxidant and anti-inflammatory properties to support reproductive health
Emotional Support and Coping Strategies
Importance of mental health and emotional well-being
Support groups, counseling, and stress management techniques
